Cock Bombs are a laboratory co-formulation of two phosphodiesterase type-5 (PDE5) inhibitors: sildenafil (shorter-acting) and tadalafil (longer-acting). Both compounds function by inhibiting PDE5, which increases intracellular cGMP in smooth muscle cells and modulates nitric oxide signaling pathways.

Research Rationale: In experimental models, combining sildenafil and tadalafil is used to study how agents with different pharmacokinetics—sildenafil with a terminal half-life of ~4 hours and tadalafil with a terminal half-life of ~17.5 hours—might produce a synergistic effect, merging rapid onset with prolonged activity for smooth muscle modulation.

For in-vitro laboratory research only. Not a drug, food, cosmetic, or veterinary product. Not for human or animal administration.