ADDITIONAL INFO

Tesofensine (NS-2330) — Research Compound

Tesofensine (NS-2330) is a centrally acting triple monoamine reuptake inhibitor (SNDRI) that blocks presynaptic reuptake of dopamine, norepinephrine, and serotonin. It is used in laboratory research to investigate monoaminergic signaling, neurotransmitter regulation, and energy-balance pathways. Preclinical studies often explore its effects on appetite control, metabolic function, and neural activity related to dopamine, norepinephrine, and serotonin.

For in-vitro laboratory research only. Not a drug, food, cosmetic, or veterinary product. Not for human or animal administration.

Product Details

• Compound Name: Tesofensine (NS-2330)

• Compound Type: Synthetic small molecule SNDRI

• Net Contents: Oral 500 mcg capsules

• CAS: 195875-84-4

• Molecular Formula: C₁₇H₂₃Cl₂NO

• Molecular Weight: ~328.28 g/mol

• Purity: ≥95% (HPLC tested; lot-specific Certificate of Analysis available)

• Solubility: Soluble in DMSO/DMF; limited solubility in aqueous buffers (see lot COA)

• Manufactured in: GMP-compliant facility

• Intended Use: Laboratory research use only — not for human or veterinary use

Storage & Handling

• Store sealed vials at −20 °C, protected from light and moisture

• Allow container to reach room temperature before opening

• Aliquot after dissolution to avoid repeated freeze–thaw

• Handle using standard laboratory sterile technique

• Consult SDS for hazards and first-aid guidance

Research Applications

Tesofensine is commonly used in research settings to study:

• Monoaminergic signaling pathways (dopamine, norepinephrine, serotonin)

• Neural and metabolic regulation in preclinical models

• Appetite control and energy-balance mechanisms

• Preclinical models of metabolic disorders

• Neurochemical modulation in in-vitro studies