ADDITIONAL INFO

Sildenafil — PDE5 Inhibitor Research Compound

Sildenafil is a selective phosphodiesterase type-5 (PDE5) inhibitor used in laboratory and preclinical research to study cGMP signaling, nitric oxide pathways, and vascular smooth muscle responses. It is commonly utilized in experimental models examining vasodilation, endothelial signaling, circulatory dynamics, and tissue oxygenation mechanisms under controlled conditions.

For in-vitro laboratory research only. Not a drug, food, cosmetic, or veterinary product. Not for human or animal administration.

Product Details

• Compound Name: Sildenafil

• CAS Number: 139755-83-2

• Molecular Formula: C₂₂H₃₀N₆O₄S

• Molecular Weight: ~474.6 g/mol

• Form: Oral 100 mg capsules

• Purity: ≥98% (HPLC; Certificate of Analysis available)

• Primary Target: Phosphodiesterase type-5 (PDE5)

• Manufactured in: GMP-compliant facility

• Intended Use: Laboratory research use only — not for human or veterinary use

Storage & Handling

• Store tightly sealed at −20 °C or as specified on lot COA

• Protect from light and moisture

• Allow container to reach room temperature before opening

• Prepare solutions using appropriate laboratory solvents

• Avoid repeated freeze–thaw after solution preparation

• Consult SDS for hazards and handling guidance

Research Applications

Sildenafil is commonly used in laboratory and preclinical studies to investigate:

• PDE5 inhibition and cGMP pathway signaling

• Nitric oxide–mediated vasodilation models

• Vascular smooth muscle response

• Endothelial signaling mechanisms

• Experimental circulation and oxygenation dynamics