ADDITIONAL INFO

MOTS-C — Research Peptide

MOTS-C (Mitochondrial Open Reading Frame of the 12S rRNA-c) is a mitochondrial-derived peptide encoded within mitochondrial DNA and expressed in cells under metabolic stress conditions. It is studied in laboratory models for its role in regulating cellular metabolism, energy utilization, and stress-response signaling. Unlike most peptides encoded by nuclear DNA, MOTS-C originates from the mitochondrial genome, making it a unique focus in mitochondrial and metabolic research.

Research has examined MOTS-C activity in pathways related to glucose handling, lipid metabolism, mitochondrial function, and adaptive cellular responses to metabolic stress. It is frequently used in preclinical models exploring exercise signaling, metabolic adaptation, and age-related metabolic changes.

Product Details

• Compound Name: MOTS-C

• Compound Type: Mitochondrial-derived peptide

• Length: 16–amino-acid peptide

• Origin: Encoded by mitochondrial 12S rRNA region

• Net Contents: 10 mg-40 mg lyophilized peptide powder per vial (varies by batch) (3mL)

• Form: Lyophilized (freeze-dried) powder

• Research Focus: Mitochondrial signaling, metabolic regulation, cellular stress response

• Purity: ≥99% (HPLC tested; Certificate of Analysis available)

• Manufactured in: GMP-compliant facility

• Intended Use: Laboratory research use only — not for human or veterinary use

Research Applications
MOTS-C is commonly used in laboratory studies involving:

• Mitochondrial communication signaling

• Glucose and lipid metabolism pathways

• Cellular energy regulation

• Exercise and endurance signaling models

• Metabolic stress adaptation mechanisms

Storage & Handling

• Store unopened vial at −20 °C

• Keep dry and protected from light

• Refrigerate at 2–8 °C after reconstitution

• Avoid repeated freeze–thaw cycles

• Handle using standard laboratory sterile technique

Research Use Notice:
Supplied strictly for laboratory research purposes only. Not intended for human consumption, medical, diagnostic, or therapeutic applications.